Ovechkin, 32, is Washington's all-time leader in goals (594) and points (1,103), and needs six goals to become the 20th player to score 600 in the League. He leads the NHL in goals this season with 36, and has 15 points (six goals, nine assists) in his past 11 games.
The Capitals, 2-3-2 in their past seven games, are in second place in the Metropolitan Division, one point behind the Pittsburgh Penguins and one point ahead of the Philadelphia Flyers.
The Sabres, 4-6-2 in their past 12 games, are in eighth place in the Atlantic Division and trail the Columbus Blue Jackets by 18 points for the second wild card into the Stanley Cup Playoffs from the Eastern Conference.