"We didn't have enough guys playing their best, but we were still there," Panthers coach Joel Quenneville said. "It was a great opportunity. It was a disappointing game to let it get away with nothing happening."
Despite owning an 11-5 advantage in shots, the Panthers entered the first intermission trailing the Sabres 1-0 after Henri Jokiharju beat Sergei Bobrovsky at the 12:49 mark of the first period.
In the second, Conor Sheary doubled the lead to 2-0 with a goal from the doorstep at 1:35. Just a few minutes later, Sam Reinhart extended Buffalo's lead to 3-0 with a power-play goal at 5:42.
After Reinhart's goal, Bobrovsky was pulled in favor of backup Chris Driedger.
Searching for a spark in the third period, Mike Matheson got the Panthers on the board when he beat Linus Ullmark with a long wrist shot to trim the deficit to 3-1 at 12:40. Then, with 1:10 left in regulation, Evgenii Dadonov lit the lamp after Florida had pulled its goaltender to make it 3-2.
Pulling their goaltender again soon after, the Panthers came very close to getting the game to overtime when Jonathan Huberdeau's shot with seconds left on the clock missed by an inch.
"I still thought that once we got one, we got two, and then we missed a great chance to get something out of this game," Quenneville said. "Maybe not deserving, but almost there."
In defeat, the Panthers once again pointed to the abundance of missed opportunities. In all situations - including three power plays - they finished with big advantages in shots on goal (34-18), shot attempts (64-35) and scoring chances (25-16), according to NaturalStatrick.com.
Driedger stopped 11 of 11 shots, while Ullmark denied 32 of 34.
"We did do a good job of limiting their chances," Matheson said. "I think our power play did a great job of generating chances, and in the third period we had a bunch of chances. It's one of those games where you look back and you feel like you played a decent game but if a couple of those shots had gone in we'd been feeling much different. At the end of the day they didn't, so we need to find ways to be better and to bury those chances when we get them."
Here are five takeaways from Saturday's loss in Buffalo…