Tage Thompson scored a pair of goals for the Sabres in a 7-4 loss to the Vegas Golden Knights inside KeyBank Center on Thursday.
Casey Mittelstadt and Rasmus Asplund also scored for Buffalo. Eric Comrie made 28 saves.
Logan Thompson made 31 saves for the Golden Knights, who were led in scoring by Jack Eichel (3+1) and Chandler Stephenson (1+3). Phil Kessel, Paul Cotter and Alex Pietrangelo also scored.
The Sabres entered the third period trailing 3-2. The Goldent Knights created separation with two quick goals, then staved off the Sabres' comeback attempts behind Eichel's four-point period.
"Too many freebees," Sabres coach Don Granato said afterward. "That was the challenge. That was the issue tonight, clearly. You trade chances with the talent that they have, it works out the way it worked out."
Buffalo has now lost four in a row and is 0-2-0 on the current four-game homestand. The team has a chance to rebound against the Eastern Conference leading Boston Bruins on Saturday.
"The sun is going to come up tomorrow," Thompson said. "It's a new day. It's a new opportunity. What's done is done. Learn from it obviously and move on. We have a good stretch of playing against good teams. Every night is going to be a challenge and that's something we need to be prepared for."
Postgame Report | Thompson scores twice in loss to Vegas
Buffalo falls 7-4 on home ice
© Ben Green