"Landy got hurt over the last couple games, he came to practice on Sunday, had some discomfort, and he went for further evaluation and he's got a lower body injury," Bednar said. "He's going to miss some significant time here."
Landeskog has appeared in 590 career contests over the course of his nine season with the Avalanche and is in his eighth as team captain. Only six other active players have been captain of their club for longer in the league.
The Avalanche forward had played in all 11 games this season, registering three goals and four assists. Last season, he produced career highs in goals (34), assists (41) and points (75) while also being named to his first NHL All-Star Game.
He was joined at 2019 All-Star Weekend with his linemates, Nathan MacKinnon and Mikko Rantanen, but the two-thirds of Avs' top trio is now out of the lineup and on the mend. Rantanen is week-to-week with his own lower-body injury that occurred on Oct. 21 at the St. Louis Blues.
Forward Colin Wilson also left Tuesday's practice with an unspecified injury.
"That's hockey. We're not going to sit here and feel sorry for ourselves," said Nazem Kadri, who practiced in Landeskog's spot on a line with MacKinnon and Joonas Donskoi on Tuesday. "They're hard guys to replace, and I'm not sure if we can replace them, but we have good enough guys in this dressing room to step up and answer the bell and produce temporarily."