Colorado took a 2-1 lead at 7:49 of the middle frame as Nathan MacKinnon split a pair of defenders off the rush and beat Corey Crawford top corner on the blcoker side with a shot mid-stride.
Andre Burakovsky made it a two-goal lead shortly thereafter, picking up a deflected puck in the neutral zone and skating in, taking a wrist shot from the dot through an Olli Maatta screen and past Crawford at 10:08 of the second.
After a back-and-forth third period, the Avs added an empty-netter at 17:04 to put the game away, 4-1.