After taking over behind the bench, Berube led the team to a 38-19-6 regular-season record and a third-place finish in the Central Division. From Jan. 1 through the end of the regular season, the Blues went 30-10-5, accumulating the most points among all teams in that span. Berube helped the Blues become just the seventh team since 1967-68 to earn a postseason berth after being last in the NHL standings at any point after New Year's Day. He also coached the Blues through a franchise-record 11-game win streak from Jan. 23 to Feb. 19 and a 12-1-1 mark in February, which tied a franchise mark for wins in a calendar month.
For his efforts, Berube was named a finalist for the 2019 Jack Adams Award - the first nomination of his career. Berube originally joined the Blues as an associate coach on June 15, 2017.
Prior to joining the organization, he made head coaching stints with the Philadelphia Flyers (2013-15), as well as the American Hockey League's (AHL) Philadelphia Phantoms (2006-08) and Chicago Wolves (2016-17).