Schenn missed practice due to the birth of his son, Huxley Michael Schenn, who arrived Wednesday. Saad missed practice with an illness, but he was back on the ice Friday for an optional team practice and is good to go, according to Blues Head Coach Craig Berube.
With both players not missing any time, no changes are expected to the forward lines or defense pairs.
Ville Husso will be back in goal after Jordan Binnington played in Tuesday's 4-1 win against the Philadelphia Flyers.
The Blues, who went 3-0-1 on their four-game road trip, will host the Sabres before returning to a four-game road trip.