Drouin extended the lead to 3-0 with a power-play goal at 14:43. Alexey Toropchenko cleared a loose puck during a scramble in front of the net right to Drouin, who beat Hofer glove side from the right circle.
“The goalie's just kind of out of his net, so I shot it right away,” Drouin said. "It's nice to get two goals on the power play. Our power play hasn't been great lately.”
Makar made it 4-0 at 17:25 with another power-play goal, this one coming on a wrist shot through a screen from above the circles.
Colorado outshot St. Louis 21-6 in the first period.
“Didn't start on time. [It's been] multiple games in row now and it costs us,” Blues captain Brayden Schenn said. “I just think the battle level has to come up early and be ready to start. You give them time and space and you give them opportunities to score goals -- and I'm not just talking tonight, previous games, too -- teams are good, players are good, and they're going to make it happen.”
Kiviranta pushed it to 5-0 at 13:21 of the third period, roofing a wrist shot glove side from the low slot.
NOTES: Forward Nathan MacKinnon had the primary assist on Makar’s goal, his 60th of the season. He is the third player in Avalanche/Quebec Nordiques history to have three consecutive seasons with at least 60 assists, joining Peter Stastny (six from 1980-81 to 1985-86) and Joe Sakic (three from 1989-90 to 1991-92). … Blues defenseman Ryan Suter played in his 1,496th game, moving him ahead of Phil Housley for seventh among defensemen in NHL history.