Ryan O'Reilly will begin his first season as the team's captain, while Brayden Schenn, Colton Parayko and Vladimir Tarasenko (injured) will serve as assistants.
Due to COVID-19 protocols, NHL teams will be permitted to carry a taxi squad during the 2020-21 season. The taxi squad will be able to practice and travel with the team and will be available in the event that players on the main roster are unable to play.
In addition, the Blues assigned 16 players to the Utica Comets, who is serving as the team's AHL affiliate during the 2020-21 season. The players assigned to Utica are Sam Anas, Evan Fitzpatrick, Jon Gillies, Dakota Joshua, Tanner Kaspick, Hugh McGing, Curtis McKenzie, Jake Neighbours, Scott Perunovich, Evan Polei, Mitch Reinke, Steve Santini, Nolan Stevens, Tyler Tucker, Nathan Walker and Jake Walman.
Matthias Laferriere has been assigned to Blainville-Boisbriand Armada of the Quebec Major Junior Hockey League.