Grabbing a point in the shootout setback, the Ducks have now earned points in two of their last three games (0-1-2) but also pushed their winless streak to five (0-3-2). Anaheim now sits 6-17-2 on the season and 2-10-3 on the road.
Troy Terry (1-1=2), Trevor Zegras (1-1=2) and Mason McTavish (0-2=2) led the Ducks offensively with multi-point efforts. Cam Fowler and Ryan Strome also scored. Dmitry Kulikov, Adam Henrique and Frank Vatrano added assists.
John Gibson made 43 saves in the defeat, his fifth 40-save performance of the season.
Caleb Addison, Connor Dewar, Joel Eriksson-Ek and Kirill Kaprizov scored for the Wild, who improved to 12-9-2 on the season and 7-6-1 on home ice.
Goaltender Filip Gustavsson made 29 saves for his third straight win, the 14th of his NHL career.
Both sides had their share of chances throughout a wide-open first period, combining for 23 shots on net, but it would be the Wild taking a 2-1 lead back to the locker room.
Addison put Minnesota ahead first less than five minutes after puck drop with his fourth career NHL goal, blasting a one-timer off a low-to-high pass by Marcus Foligno that hit an Anaheim defender in front and deflected past Gibson.
The 22-year-old Addison, who added an assist later on, has carved out a prominent role on the Wild defense this season, now with 2-11=13 points in 23 games. He leads club blueliners in points, assists and power-play points (nine).
Foligno, son of former Ducks assistant coach Mike Foligno, drew the primary assist and now has points in his last four matchups against Anaheim.
The Ducks responded just four minutes later, pulling back even when Vatrano spun away from trouble just inside the Wild blue line and fired the puck on net, where Strome got inside positioning on defenseman Jon Merrill and redirected the shot between Gustavsson's legs.