Burns is first among NHL defensemen with 52 points (nine goals, 43 assists). Karlsson is tied for fourth with 43 points (three goals, 40 assists.
Pavelski, who leads the Sharks and tied for 12th in the NHL with 26 goals, was chosen for his third All-Star Game.
"It's been a couple for me now," Pavelski said. "It's been fun. It'll be different in our hometown. Just excited to be a part of it."
The Colorado Avalanche and Tampa Bay Lightning will also have three players apiece in the game. Colorado forwards Nathan MacKinnon and Mikko Rantanen were selected by hockey operations on Jan. 2, and linemate Gabriel Landeskog was voted in by the fans in the Last Men In presented by adidas. Tampa Bay forwards Nikita Kucherov and Steven Stamkos were selected to the Atlantic Division roster and goalie Andrei Vasilevskiy was named as a replacement for Montreal Candiens goalie Carey Price.
The reigning Stanley Cup champion Washington Capitals will have two players on the Metropolitan Division team: defenseman John Carlson and goalie Braden Holtby.
"It was nice, it was good to be recognized," Carlson said. "Just another experience that I can enjoy and it's pretty cool. I wasn't going to be upset if I didn't (get selected). It wasn't going to change anything about me as a player, but these things are fun experiences and I'm glad I get to share it with Holts as well. That'll be another little cool experience that I'll have with him. We've been together a long time and obviously he deserves it a lot too and many guys in this room deserve it as well."
Other teams with two players selected are the Columbus Blue Jackets (forward Cam Atkinson, defenseman Seth Jones) and the Pittsburgh Penguins (forward Sidney Crosby, defenseman Kris Letang) in the Metropolitan Division; the Toronto Maple Leafs (forwards Auston Matthews and John Tavares) and the Buffalo Sabres (forwards Jack Eichel and Jeff Skinner) in the Atlantic Division; and the Winnipeg Jets (forwards Mark Scheifele and Blake Wheeler) and Nashville Predators (defenseman Roman Josi and goalie Pekka Rinne) in the Central Division; and the Edmonton Oilers (forwards Connor McDavid and Leon Draisaitl) in the Pacific Division.
Carlson, Rantanen, Landeskog and Scheifele are among 13 players who will be playing in their first All-Star Game. Also in that group is Vancouver Canucks forward Elias Pettersson, who leads NHL rookies with 22 goals and 42 points.
"All the stars in the NHL are there, and the players I've been growing up watching, now I'm going to be at the All-Star Game with them, so I'm very happy with that," Pettersson said.
Chicago Blackhawks forward Patrick Kane will play in his eighth All-Star Game, most among players in this year's game.
Crosby will make his fourth appearance, including three straight.
"It's an honor to be selected," Crosby said. "You look around the League, a lot of guys having great years ..."
It will be the first All-Star Game appearance since 2012 and third overall for Florida Panthers defenseman Keith Yandle.
"It's obviously very humbling, especially with the amount of talent there is in the game, on our team, everywhere," he said. "Looking at the rosters, it's one of those things you pinch yourself a little bit but obviously excited to represent our team."
