Rickard Rakell tied the game 1-1 at 4:52 of the third period when a rebound of Hampus Lindholm's shot went in off his body following a turnover by Bertuzzi.
"You need to make the simple play there," Detroit coach Jeff Blashill said. "Tyler didn't have a great game, and that's part of the pressure of being part of a top line where you can't take nights off."
Larkin appeared to give the Red Wings a 2-1 lead at 8:06, but Eakins challenged the play for offside, and the call was reversed after video review.
"Obviously, that was a massive swing in the game," Eakins said. "Our video guys made a heck of a call there. I hate doing that, because the linesmen work so hard, but that was one we had to challenge."
Said Larkin, "Our response after the goal was waved off just wasn't good enough. We weren't pushing in the O zone and we weren't getting back on defense."