Zadorov was injured when he collided with forward Mikko Rantanen. Zadorov, a 21-year-old rookie, has 10 assists in 56 games this season.
"He actually fell on top of Mikko, but his leg got trapped underneath Mikko and he fell awkwardly," coach Jared Bednar told the Avalanche website.
Avalanche defenseman Erik Johnson, who has missed 33 games because of a broken leg, practiced Monday in a no-contact jersey. Johnson was injured while blocking a shot from Dallas Stars forward Tyler Seguin on Dec. 6.
"He's improving and we'll just see what tomorrow brings," Bednar said. "He's had some days where he's felt real good and others not. Seems to be on the right path, and hopefully he'll be joining the team for full practice here in the next few days."