The Avalanche game against the Minnesota Wild scheduled for Thursday was previously postponed due to COVID-19 issues with the Wild.
In addition, Avalanche games at the St. Louis Blues on Saturday and Sunday, and home games against the Arizona Coyotes on Feb. 9 and Feb. 11 have been postponed.
Forwards Tyson Jost and Gabriel Landeskog were the Avalanche on the NHL protocol list as of Saturday.
The Colorado training facility is closed. The NHL is reviewing and revising the Avalanche regular-season schedule.
Minnesota, which lost 2-1 at Colorado on Tuesday, had five players added to the protocol Wednesday, when the NHL postponed the next four Wild games, through Feb. 9.
The Coyotes and Blues, who played each other Tuesday and Thursday, were subsequently rescheduled to continue their series at St. Louis on Saturday and Monday. Those games have been rescheduled from March 29 and March 31.
The NHL has postponed 24 games during the 2020-21 season; two were postponed prior to its start.