Murray forced the shootout by denying Eichel on a breakaway with 28.1 seconds remaining in overtime. Eichel attempted the same move on his breakaway and shootout attempts, but Murray said the situations were slightly different.
"I think the backpressure makes it a bit different," Murray said. "You come in with a little more speed when there's a guy riding your tail and in the shootout, you can come in slow, say like [Letang] did, and that can throw off a goalie pretty bad. So, same kind of idea, but you just want to try to stay on top of him and try to force him to make the first move."
The Penguins (43-25-8) are one point behind the New York Rangers for second place in the Metropolitan Division after handing the Sabres (31-35-11) a second loss in as many nights.
Facing a 3-0 deficit, Penguins defenseman Ben Lovejoy began a four-goal surge with his fourth goal of the season 1:28 into the second period to cut the Sabres' lead to 3-1.