"Our penalty kill was solid, great double-minor penalty kill in the second," Buffalo coach Phil Housley said, referring to the high-sticking call against Johan Larsson at 11:45. "But when you get into those penalty situations, it disrupts our bench and the flow of our lines."
The Sabres and Lightning combined for five goals in the first period.
Girardi gave Tampa Bay a 1-0 lead at 2:59 when he followed up his own shot after Killorn set up him up in the low slot.
"I thought it was a really good first period, really physical and in each other's faces," Girardi said. "On the goal, somehow I got down there and no one covers me. [Killorn] made a great play and gave me a good look."
Zemgus Girgensons tied it 1-1 at 8:42 when he tipped a Rasmus Ristolainen shot.
Reinhart gave Buffalo a 2-1 lead at 9:45 with a shot that bounced off Domingue's shoulder.
"When you go on a streak like that, teams are going to take notice and be ready for you and they certainly were tonight," Reinhart said. "We have another opportunity, another crack at it to get two more points tomorrow."
Killorn tied it 2-2 at 10:28 when he put in the rebound of a J.T. Miller shot.