The Maple Leafs, 3-1-0 in their past four games, have scored at least five goals in each of the three victories. Toronto is three points behind the Boston Bruins for second place in the Atlantic Division.
Nic Petan will make his Maple Leafs debut. The forward, acquired in a trade with the Winnipeg Jets for center Par Lindholm on Feb. 25, had two assists in 13 games with the Jets this season.
The Sabres, 2-5-1 in their past eight games, trail the Columbus Blue Jackets by seven points for the second wild card into the Stanley Cup Playoffs from the Eastern Conference.