Gudbranson's first goal of the season pushed the lead to 5-0 at 6:55, and Tkachuk's 20th of the season made it 6-0 at 7:36.
Gudbranson had not scored in 60 games since Feb. 25.
"I scored against Calgary. I was playing for [the] Ottawa [Senators]," said Gudbranson, who has scored 22 goals in 601 NHL games. "I have so few of them that, yeah, I do remember. It's not my job, but if you can chip in that way it's always nice."
NOTES:Calgary had the most shots against Columbus in a regular-season game. The previous high allowed by the Blue Jackets was 55 by the Florida Panthers on Dec. 4, 2014, in a 4-3 shootout win for Columbus. … Gaudreau has scored 14 points (two goals, 12 assists) during a six-game point streak. … Lindholm has scored four points (two goals, two assists) during a four-game point streak. … Flames defenseman Rasmus Andersson had an assist to extend his point streak to four games (four points; one goal, three assists). … Mangiapane set an NHL career high with his 19th goal through 38 games; he scored 18 last season 56 games. … Columbus defenseman Adam Boqvist played 18:14 in his return after missing three games in NHL COVID-19 protocol. … Blue Jackets forward Alexandre Texier did not play after the first period because of an upper-body injury. Larsen said he would be out a "little bit here."