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Columbus (45-30-7) will be the first wild card into the Stanley Cup Playoffs from the Eastern Conference and play the Washington Capitals, who won the Metropolitan, in the first round.
"I thought the effort was great tonight, so that's pretty much all we're going to carry over for [Washington]," Blue Jackets forward Thomas Vanek said. "I'm sure we'll have [Sunday] off, I'm guessing, and then we'll go back to work on Monday and get focused on them. It's going to be a tough series."
Nashville (53-18-11), which had clinched the Presidents' Trophy, Western Conference and Central Division, will play either the Colorado Avalanche in the first round.
"I think everybody is really excited for the playoffs, but we know how hard of a road it is in the playoffs," Predators captain Roman Josi said. "But the excitement is definitely here. It's always a long season toward the end. You're really excited for the playoffs, and we can't wait for the first game."
Predators forward Filip Forsberg scored his fifth career NHL hat trick.