The Blue Jackets (12-8-0) were shut out for the second time this season. Elvis Merzlikins allowed three goals on nine shots and was replaced at 12:52 of the first period by Joonas Korpisalo, who made 25 saves.
"Not a good start by us," Blue Jackets forward Boone Jenner said. "We couldn't make plays. We were not as sharp and as quick as we wanted to be throughout the night, but the start definitely hurt us."
Forsberg gave the Predators a 1-0 lead at 4:56 of the first period. He skated in along the bottom of the left circle and shot short side over Merzlikins shoulder.
"I think our line started off really well in the first, and obviously got one early, had a lot more chances," Forsberg said. "Both [Granlund] and [Duchene] played incredible. Made life very easy for me. I was able to finish off some of their plays, obviously, and it was good."
Yakov Trenin made it 2-0 at 12:43, and nine seconds later, Forsberg extended the lead to 3-0 with a shot from the slot following a Columbus turnover.