Dreidger's third start of the season was the sixth NHL game of his seven-year professional career. His best save came during a busy first period when he lunged across the crease to stop a rebound by Warren Foegele.
"It felt like a lot of scrambly plays, and I just tried to stay behind them," the 25-year-old goalie said. "[Carolina] had a lot of shots through traffic, but our guys did a great job blocking shots. We just kind of built our game from there."
Acciari drove to the right circle for a wrist shot that gave the Panthers a 4-1 lead at 10:41 of the third period. It was his seventh goal in three games, including a 7-4 win against the Dallas Stars on Friday.
Evgenii Dadonov took Boyle's stretch pass and scored on a breakaway with a shot over Mrazek's blocker for a 1-0 lead at 7:07 of the first period.
Boyle redirected Aaron Ekblad's shot from the left point for a power-play goal to put the Panthers up 2-0 at 11:34 of the second period. Boyle did not have a point in the previous 10 games.
"When we get power-play opportunities on the road on a back-to-back, I won't say it's more important, but you really want to execute and steal momentum," Boyle said. "I think we did a good job of that."
Huberdeau extended the lead to 3-0 with a power-play goal at 26 seconds of the third period. He drew Mrazek out of position, drifted away from the slot and scored into an open net.
"It certainly helped getting that one right off the bat in the third to get a three-goal lead," Quenneville said. "[Carolina] is dangerous, and they press and they had some great zone time."
Carolina made it 3-1 at 9:16. Driedger stopped Dougie Hamilton's shot from the right point, but Niederreiter scored on the rebound. Niederreiter set up Wallmark below the right circle to make it 4-2 at 12:59.
"The boys kept battling," Hurricanes captain Jordan Staal said. "I love that we don't go away. We tried to find a way to win the game, but we came up short tonight."