The Panthers (16-5-4) have one regulation loss in seven games (4-1-2) and are 8-2-0 in their past 10 road games.
"It was a good game definitely," Bobrovsky said. "I faced lots of shots, and the guys really helped me there. And I knew that Columbus is a really good, hard working [team] and they're going to put the puck on the net and work around the net."
Oliver Bjorkstrand and Michael Del Zotto scored, and Joonas Korpisalo made 29 saves for the Blue Jackets (10-12-5). Columbus has two wins in its past nine games (2-6-1).
"Offensively I thought after the first few minutes of the game, where it was a struggle, we started to play the right way," Columbus coach John Tortorella said. "I thought we moved on. I hated the second period defensively. Hated how we defended in the second period. Hated how soft we were in the second period defensively.
"On the other end, we played really well offensively but we just can't defend that way, period, in that that second period. We cannot defend that way."
Juho Lammikko scored at 4:59 of the first period to give the Panthers a 1-0 lead.
Bobrovsky made a left skate save on Cam Atkinson, who had shorthanded breakaway at 7:45 of the first.
"He was unreal tonight," Lammikko said of Bobrovsky. "A lot of huge saves, especially in the third. He gets the lead, and it was fun to watch him. It was awesome."