Verhaeghe scored on a delayed penalty to extend the lead to 3-1 at 8:09 of the third period, redirecting a centering pass from Barkov.
"Detroit came out strong and scored right off the bat, but we caught up to the pace," Florida coach Joel Quenneville said. "We got a couple of lines going, and that's important for us. We're not a one-line team."
Mantha cut it to 3-2 at 18:12 with Greiss pulled for the extra skater, but the Panthers held on for their eighth straight win against the Red Wings.
NOTES:The Red Wings have five players in NHL COVID-19 protocol (defenseman Jon Merrill and forwards Adam Erne, Robby Fabbri, Sam Gagner and Filip Zadina), but Blashill said he expects to have each player back for Detroit's upcoming two-game set against the Tampa Bay Lightning on Wednesday and Friday. ... Ekblad, who was born across the Detroit River in Windsor, Ontario, has scored 16 points (three goals, 13 assists) in 24 games against the Red Wings, his most against any opponent.