WATCH: All Panthers vs. Oilers highlights
"I thought it went in just because [Reimer] was already in his net, basically," McDavid said. "The refs did a good job and the guys back in Toronto doing the video [review] did a good job to find a clear shot of it."
McDavid took a long pass from Leon Draisaitl and made a move before shooting the puck to Reimer's left.
"I don't think any goalie will agree with that call," Reimer said. "Obviously he's a good player, and I think 20,000 people thought it went in and I knew I had it in my glove. I didn't know if it crossed the line or not, but when I saw the replay I thought they might call it our way, but it was not the way the refs saw it, so you just go on with life. I'll take from it what I feel I can and just move on."
Vincent Trocheck, Michael Sgarbossa and Greg McKegg scored for Florida (20-18-9), and Reimer made 27 saves.
"The video is clear, they had a view of it in Toronto, they had a view of it right on the ice, so we're going to go with it," Panthers coach Tom Rowe said. "[Referee] Francis [Charron] made the right call as tough as it is. Talking to [goaltending coach] Robbie Tallas after the game, he said it was definitely in. The NHL does a real good job looking at the video review, it's tough, but you have live with the ruling."
Zack Kassian, Mark Letestu and Jordan Eberle scored for Edmonton (25-15-7), and Cam Talbot made 28 saves to extend the Oilers' winning streak to four games.