Huberdeau cut it to 3-1 on the power play at 2:47 of the second period.
"At 3-1 we had a little chance, but we took some penalties … and it just didn't go our way tonight," Huberdeau said. "We have to forget about this one."
Alex Killorn made it 4-1 with a power-play goal at 5:53, scoring on the rebound of a shot by Steven Stamkos. Six of Killorn's goals this season have come on the power play.
"The big thing for [Killorn] is when he's skating and using his body he can be very effective," Cooper said. "[He] has been really determined this year. He's going and getting pucks. He's been dynamite around the net, and he's been great on the power play. He's been fun to watch."
Kucherov scored on the power play to make it 5-1 at 9:52.
Hedman scored his second goal at 18:05 of the third period for the 6-1 final.
"We love these kinds of games, they are important games for the team, and we like to be in these situations," Hedman said. "We have to rise to the occasion. We did that today, and we have to do that in the upcoming games as well."
Panthers defenseman Aaron Ekblad left the game midway through the second after taking a shot on the shoulder, and Florida defenseman Anton Stralman left at 5:18 of the third with a facial laceration after a shot hit him in the top of his helmet. He received stitches for the cut.
"We'll see how [Ekblad] is," Panthers coach Joel Quenneville said. "Going into the Christmas break and coming out of it with three days [of rest] is going to be good for him and good for us. But coming back with the back-to-back games (Saturday and Sunday), we're probably not sure about those games right now."