Pietrangelo had a goal and an assist, and Sammy Blais scored for the Blues (7-3-3), who have won four of their past five games, including a 5-4 overtime victory at the Detroit Red Wings in their previous game.
"A team coming off back-to-backs," Pietrangelo said of Minnesota, which lost 6-3 at the Dallas Stars on Tuesday. "I think we had moments where we controlled the game, but I think we can be a little more aggressive when we have teams that come in late and play. We know what it's like playing those back-to-backs. It's not easy. I said it to you guys in Detroit on Sunday], this is a couple games in a row, we just found a way to win, but I think it's time for us to start stringing things together here."
***[WATCH: [All Wild vs. Blues highlights]*
Devan Dubnyk made 24 saves, and Mats Zuccarello scored his first goal with the Wild (4-9-0), who are 1-8-0 on the road.
"Of course it's concerning," Minnesota coach Bruce Boudreau said. "I mean, 1-8 or whatever we are, anytime on the road, it's concerning. It'd be concerning if it were at home. Whether it's at home or on the road, it's just that 1-8 part people keep looking at.
"I think there's games we've played pretty good on the road and haven't gotten the results we'd like to get, but I think in defeat, this was a really positive thing for us, and if we can build off of this, we've got them again on Saturday and it's not going to be easy. But if we can build off of it, that's what we want to do."