It was Skinner's first goal this season.
"It's always nice, obviously, if you haven't got one in a while to get one to maybe relax a little bit," he said. "But yeah, after that you kind of look forward to the next one, and I thought we had some chances, just couldn't get that one we needed."
The Sabres controlled play for most of the second, ending the period with a 13-9 advantage in shots.
"I think the second period was our big, big opportunity," Buffalo coach Don Granato said. "I think there we complicated some things. We could have been a little bit more intense going to the net, maybe scored a goal. I think we tried to pass the puck into the net. Feeling good about puck movement of possession time and didn't have the killer instinct that we needed at that point, and it caught up with us."
Guhle put Montreal back in front 2-1 at 6:51 of the third period, scoring on a one-timer from below the right face-off circle.
"The win's obviously the most important part," Guhle said. "I'm just trying to do whatever I can to help the team win. So it was nice to see that one go in, but it was obviously a big win for us tonight and a good way to start the (four-game) road trip."