Quick was acquired by Vegas in a trade with the Columbus Blue Jackets on Thursday, one day after he was traded to the Blue Jackets by the Los Angeles Kings for goalie Joonas Korpisalo and defenseman Vladislav Gavrikov.
"I felt pretty comfortable right from the get-go," Quick said. "Obviously, just a different setting. Different color jersey. Once you get out there, you're just trying to play hockey."
Ivan Barbashev scored twice for the Golden Knights (38-19-6), who have won three straight and are 9-1-2 since the All-Star break.
Vegas moved two points ahead of Los Angeles for first place in the Pacific Division.
"It's a result-oriented business. We won the hockey game. We've won some very close games," Golden Knights coach Bruce Cassidy said. "Momentum swings both ways. As a coach, you're hoping they go more your way than the other team's way more consistently. … It's not easy to win in this league. I'm a glass half full type of guy, so I appreciate the points, but I'm also a coach, so I'm also looking at correcting."