Karlsson will play for Sweden in the 4 Nations Face-Off. He leads Penguins defensemen with 35 points (five goals, 30 assists) in 54 games.
Crosby made it 2-0 at 10:43 of the second period with his 17th goal. He scored with a one-timer while on one knee from just below the right circle off a pass from Rakell.
“We’re trying to play a simpler, straight-ahead game,” Penguins coach Mike Sullivan said. “I just think we’re at our best when we play that way. ... I feel like our team is at its best when we’re controlling territory.”
Rust scored an empty-net goal at 17:59 for the 3-0 final.
“It’s just the little details of the game,” Nashville forward Steven Stamkos said. “You look at where we are in the standings (seventh in the Central Division), you can’t afford to have mishaps in games or as many as we’ve had the last couple nights. It costs you.”
The Predators had the shot advantage in their previous nine games, including a five-game winning streak from Jan. 14-23. They were outshot 27-16 in the final two periods Saturday.
“It’s definitely frustrating,” Nashville captain Roman Josi said. “Last month too, we had some really good stretches. It feels like you get something going. Now, obviously, it feels like we’re going through a rough stretch again. By this time, you want your game in order.”
NOTES: Saros returned after missing the game Friday with an undisclosed illness. ... Forward Danton Heinen and defenseman Vincent Desharnais each played his first game for the Penguins since being acquired in a trade with the Vancouver Canucks on Friday. Heinen, who played 141 games with the Pittsburgh from 2021-23, had three shots on goal in 12:42 of ice time; Desharnais had four blocked shots and two hits in 16:17. ... Crosby is the fourth Penguins player with a goal streak of at least four games at age 37 or older, joining Dean Prentice (two four-game streaks in 1969-70), Mario Lemieux (four games in 2002-03) and Evgeni Malkin (four games in 2023-24). He also tied Marcel Dionne and Nicklas Lidstrom for the fifth-most 40-assist seasons in NHL history (16). ... Rust reached 20 goals for the sixth straight season.