Kreider gave New York a 3-2 lead at 13:48, scoring a power-play goal on a wrist shot after Domingue failed to glove a shot from Zibanejad. Shesterkin left his crease to collect a clear from Pittsburgh forward Teddy Blueger along the wall before bouncing a stretch pass through the neutral zone to send Zibanejad in on Domingue.
"Showed some character in our group," Rangers coach Gerard Gallant said. "Being down 2-0, it wasn't looking too good in the first."
Malkin tied it 3-3 at 16:36 with a wrist shot to the glove side on a breakaway.
"I didn't see our team getting rattled. The demeanor on the bench is fine," Penguins coach Mike Sullivan said. "The conversation on the bench amongst the players is fine. I didn't see that at all. You have to give their team credit. They have a really good team over there too.
"They can score goals. I think, for the most part, we've done a good job of limiting the amount of quality looks that they're getting, but they're going to get some."
Jeff Carter put the Penguins ahead 1-0 at 14:12 of the first period. He scored on a backhand off the rebound of a backhand from Kasperi Kapanen.
Bryan Rust made it 2-0 at 15:48, dropping to one knee for a one-timer from a sharp angle off a cross-ice pass from Jake Guentzel.
"I think the issue has more been the second period, where we get on our heels a little bit and can't capture our game quick enough," Pittsburgh defenseman Mike Matheson said. "They're going to have their pushes. They might score one or two. I think we need to do a better job of not getting rattled in those situations and just staying the course."
NOTES: Crosby skated with skills coach Ty Hennes before the morning skate Friday. His status for Game 7 has not been disclosed. The Penguins played a playoff game without Crosby for the first time since May 3, 2017, a 3-2 win against the Washington Capitals in Game 4 of the second round. Pittsburgh won that series in seven games and went on to win the Stanley Cup for a second straight season. … Zibanejad had three points (two goals, one assist) in the second period, tying the most points by a Rangers player in one playoff period. J.T. Miller was the last New York player to have three points in a period during the playoffs, with three assists in Game 2 of the 2016 first round against Pittsburgh. … Penguins forward Brian Boyle left with a lower-body injury after hitting Rangers defenseman Jacob Trouba. His last shift ended at 7:45 of the first. … New York forward Tyler Motte had one shot on goal and two hits in 9:32 of ice time in his first game since sustaining an upper-body injury against Pittsburgh on April 7.