The New Jersey Devils center replaces teammate Kyle Palmieri, who has an injured left foot. Palmieri, a forward, did not play in a 3-1 win against the Tampa Bay Lightning on Sunday with the injury sustained in a 5-1 win against the Washington Capitals on Saturday.
"Really excited," Hischier said. "Obviously you don't like to see a teammate getting hurt, so I'm sorry for Palmieri, but he texted me and told me it's going to be a fun weekend for me and I've got to enjoy it, so I really appreciated that."
The No. 1 pick in the 2017 NHL Draft, Hischier is second on the Devils with 28 points (12 goals, 16 assists), three behind Palmieri. The 21-year-old has 10 points (six goals, four assists) in his past nine games.
In 191 NHL regular-season games, Hischier has 127 points (49 goals, 78 assists).
"It's well deserved," New Jersey coach Alain Nasreddine said. "We've been talking about Nico a lot lately and he's taken that next step on and off the ice so it's nice to see him getting rewarded and going to the All-Star Game."
This is his first NHL All-Star Game appearance and he will take part in the 2020 NHL All-Star Skills on Jan. 24.
"Being able to represent my team down there, it's going to be fun," Hischier said. "It's kind of a dream come true. Growing up I always watched the All-Star Game, so it's pretty cool, I'm pretty excited about it.
"Obviously there's going to be the best players in the League there. Getting to know them and being around them is going to be really helpful for sure for me."