Matthews leads the NHL with 31 goals and is on pace for 40 this season, which is 56 games. He would be on pace for 62 goals in a normal 82-game season.
"It felt really good, it felt really good," Matthews said. "Those two guys (Mitchell Marner and Alex Galchenyuk) were making plays all night, and I was fortunate to be on the receiving end of a couple nice passes and I just had to put it in the net."
Jack Campbell made 27 saves for his 11th straight win, setting the NHL record for the most to start a season, and Marner had a goal and three assists for the Maple Leafs (28-10-3), who have won six in a row and are 9-0-1 in their past 10.
"Oh I definitely owe the boys a nice Red Lobster dinner, that's for sure," Campbell said. "Definitely not what I expect out of myself, but thankfully we have a great team and they carried me tonight. It was a fun game honestly, it's not fun giving up goals and I expect more out of myself, but Ottawa really came to play. The guys played so well in front of me tonight."
Connor Brown set an Ottawa record with a goal in his seventh straight game and had an assist for the Senators (13-25-4), who have lost four straight.
Tim Stutzle
and Drake Batherson each had a goal and an assist, and Anton Forsberg made 32 saves.
"A lot of great plays, but a lot of learning lessons as well," Senators coach D.J. Smith said. "You get a lead, you've got to protect it. We were careless with the puck against their top line and they burn you. We fought to the end, but you've got to take care of the puck a lot better against some of the best players in the League."