Luongo was up to the task early. He denied Jets right wing and Finnish sensation Patrik Laine with a glove save on a wrist shot from the left face-off circle 4:15 into the first period.
He kept the Panthers within a goal at 4:35 of the second period when he gobbled up Jets center Mark Scheifele's shorthanded chance on a 2-on-1. Forward Mike Hoffman scored 24 seconds later to tie it 2-2.
And then in the third, Luongo was the best player on the ice. He made 17 saves and secured a much-needed victory.
"It's tough. I went through it last year," said Luongo, who missed more than two months because of a groin injury last season. "It's never fun to be watching on TV while the guys are playing and you're sitting. I was working hard trying to come back as soon as possible. I wish I could have come back even sooner, but it is what it is.
"We definitely didn't want to go back home with two losses; we wanted to get the split," Luongo said. "They're a good team on the other side and we knew that to win it would have to take a special effort. I thought everybody chipped in tonight. It was great."
His teammates are certainly relieved to have him back.
"You guys all saw it, how good of a goalie he is," Panthers captain Aleksander Barkov said. "[James] Reimer has been really good the last couple of games and when we get that type of goalie like [Luongo] back, it's not only on the ice, it's in the locker room too.
"He gives us a lot of confidence. He's telling us what to do, he talks a lot on the ice and off the ice."