Pavelski has four points (two goals, two assists) in seven Stanley Cup Playoff games. He led the Sharks with 38 goals and had 64 points in 75 regular-season games.
"Obviously getting him back in the lineup will be a big boost for our team and will give us another real potent player offensively with the right-side draws and the penalty kill," Sharks forward Evander Kane said. "He just does so much, so obviously looking forward to that, but we have a real tough game in Colorado in Game 6 that we want to close out."
Pavelski was on hand to watch the Sharks in Game 5 and waved a rally towel to pump up the crowd in the third period.
"I was excited to get out there," Pavelski said. "Once I got out there and saw the crowd and the energy and got into it, you realize how much you miss it. ... These fans are special to me and this group, they always have been."
The Avalanche said they will approach Game 6 the same with or without Pavelski in the Sharks lineup.
"He is an all-star and he is one of the best players on their team," Colorado captain Gabriel Landeskog said. "I don't know exactly how old he is -- he's north of 30 and he's putting up points and producing every year, year in and year out. I mean, he's an elite player. Obviously, he's their captain, and he means a lot to their group. You just saw how they rallied in Game 7 against the Golden Knights. So I'm sure there will be a boost for them.
"But for us, it doesn't change anything. We prepared going into the series as if he was going to play, and to be honest, we don't really care who is in or who is out for them."
NHL.com staff writer Tim Campbell contributed to this report