Dylan Strome had a goal and an assist, and Alex DeBrincat had three assists and scored the only goal in the shootout for the Blackhawks (25-38-11), who were 0-6-2 during their eight-game skid. Kevin Lankinen made 33 saves.
"Feels good," Kane said. "Obviously, (it) changes the vibe in the room a little bit when you win a game. Everyone's excited, everyone's upbeat in the room after that one and it's nice to get two points on a night like tonight too."
Timo Meier had a goal and an assist for the Sharks (29-33-11), who have lost eight in a row (0-5-3) and were eliminated from Stanley Cup Playoff contention. James Reimer made 28 saves, including four in overtime.
"Guys playing hard and being in the fight until middle of the season, I think we ran into about a month-and-a-half where we had seven, eight, nine veterans out of the lineup," San Jose coach Bob Boughner said. "If you're behind the race after Christmas, you guys (the media) know this, it's not a good sign statistically. We just couldn't stay healthy. When we did, we battled, we played hard, we were in a lot of games."
Kane scored at 1:18 of the first period on a 3-on-1 rush with DeBrincat and Strome to give Chicago a 1-0 lead.
"A weird game," Boughner said. "We go out there and have a great first shift, have some great chances. Turnover (by Brent Burns) leads to a 3-on-1 goal. Not the guy you want on the back door tapping it in."