It was Husso's first career start in the Stanley Cup Playoffs. He is the first goalie in Blues history to get a shutout in his postseason debut.
"It feels good to get the win, for sure," Husso said. "I was a little nervous before, like normally, but got a good start for the game. Guys battled hard. The penalty kill was unreal. Power play was good (2-for-6), so it was a big win for us."
Ryan O'Reilly had a goal and an assist for St. Louis, the No. 3 seed in the Central Division, which was 6-for-6 on the penalty kill. Torey Krug had three assists.
Game 2 will be played here Wednesday.
RELATED: [Complete Wild vs. Blues series coverage]
"[The] next game, I think it's going to be a lot different," Perron said. "If they grab the first goal tonight, it's probably a different game. It's huge in playoffs to get the first one. We've just got to turn the page and get ready for the next one."
Marc-Andre Fleury made 27 saves for the Wild, the No. 2 seed in the Central.
"That's our season," Minnesota coach Dean Evason said. "Our special teams has not been very good. … For us to have success, we've got to stay out of the box and we've got to play 5-on-5 because we really, really liked our game 5-on-5."