Jack Campbell made 20 saves for the Maple Leafs (35-14-7), who had a nine-game point streak end (7-0-2). Toronto is the No. 1 seed in the North and will play the Montreal Canadiens, the No. 4 seed, in the first round beginning Thursday.
"It's pretty cool," Maple Leafs forward Wayne Simmonds said. "Original Six rivalry and it's the Leafs versus the Canadiens. I'm extremely excited to be part of this series. I just can't wait to get it started. … It's going to be a blast."
Toronto captain John Tavares said, "I'm sure it will be intense. Obviously there's a lot to play for. A special rivalry. So I'm looking forward to being part of it and having the opportunity. We have just under a week to prepare, rest up and get ready to go. So we're excited."
Pierre Engvall gave the Maple Leafs a 1-0 lead at 7:15 of the first period with a wrist shot from high in the left face-off circle.
Mason Appleton tied it 1-1 at 1:13 of the second period from the low slot after Toronto defenseman Morgan Rielly turned over the puck deep in his zone.
"You win the last game and you're feeling better, and to get two in a row with that win tonight, it's big for our club," Appleton said. "You win two and you kind of forget about the losing streak. We're a good hockey team. … We know what we're capable of, and I think we're going to show that here as we start the postseason."
Ilya Mikheyev scored on a rebound to put Toronto ahead 2-1 at 5:25 of the second.
"I think we've got a good mix of guys in their prime, and experience," Maple Leafs forward Jason Spezza said. "I think we've gone through some hardships as a group. I think there's guys in the room, I feel like we have a lot to prove come playoff time after last year. We've been a hungry team since losing (in the Stanley Cup Qualifiers last season) to [the] Columbus [Blue Jackets], and now it's our time to show we've matured as a group, and we've played better hockey and we've focused in on things that we knew were weaknesses last year."