The last to do it was Washington Capitals forward Alex Ovechkin in 2007-08. He won the Hart Trophy after scoring 112 points (65 goals, 47 assists).
So did Mario Lemieux; the Pittsburgh Penguins icon was part of the 60-100 club in 1992-93 and 1995-96.
Teemu Selanne, Pavel Bure, Luc Robitaille and Alexander Mogilny also topped 60 and 100 in 1992-93 but couldn't best Lemieux for the Hart Trophy. Jaromir Jagr scored more than 60 and 100 with Lemieux in 1995-96.
"Sixty goals is hard," Maple Leafs forward Mitchell Marner said. "Anyone you talk to who has achieved that accomplishment knows how hard it is. He's not just putting up goals, he's putting up assists as well and doing stuff for the team to help us win and take us to a new height. It's been a lot of fun to be on that ice with him for a lot of them. It's been remarkable just seeing how hard he works every single day and he's getting better. Hopefully he does get it. He deserves it."
The field is wide open, though, and the NHL.com voting showcases how there is no consensus favorite.
Matthews won the vote with 61 points, but he received four first-place votes; Florida Panthers forward Jonathan Huberdeau, who is tied for second in the NHL with 115 points (30 goals, 85 assists), finished with 57 voting points and seven first-place votes.
Connor McDavid was third with 43 points and three first-place votes. The Edmonton Oilers center is on his way to winning the Art Ross Trophy as the leading scorer in the NHL for the fourth time; he finished with 123 points (44 goals, 79 assists) in 80 games.
Igor Shesterkin got two first-place votes and was fourth in the voting with 32 points. The New York Rangers goalie had 36 wins and five shutouts, and leads the NHL with a 2.07 goals-against average and .935 save percentage (minimum 10 games).
Nashville Predators defenseman Roman Josi received the other first-place vote, but finished sixth in the voting with 20 points, six fewer than Calgary Flames forward Johnny Gaudreau, who is tied with Huberdeau for second in scoring with 115 points (40 goals, 75 assists).
But Matthews appears to be generating the most buzz on the national level for the Hart Trophy.
"Auston Matthews is my Hart Trophy winner," NHL Network and TSN analyst Mike Johnson said on the "NHL @TheRink" podcast last week. "Even though Auston missed some games (eight), his points per game (1.45) is virtually the same as the guys who are ahead of him (in points).
"So if you have the same number of points, you just missed a few games, and you scored more goals and you're on a team that's going to put up 114 points, and if you care about defensive metrics he is a better defensive player than Connor McDavid, a better defensive player than Jonathan Huberdeau. Don't sleep on Johnny Gaudreau, he deserves a lot of conversation here, but it's Auston Matthews for me."
Voting totals (points awarded on a 5-4-3-2-1 basis): Auston Matthews, Toronto Maple Leafs 61 points (4 first-place votes); Jonathan Huberdeau, Florida Panthers, 57 (7); Connor McDavid, Edmonton Oilers, 43 (3); Igor Shesterkin, New York Rangers, 32 (2); Johnny Gaudreau, Calgary Flames, 26; Roman Josi, Nashville Predators, 20 (1); Kirill Kaprizov, Minnesota Wild, 8; Cale Makar, Colorado Avalanche, 4; Alex Ovechkin, Washington Capitals, 2; Sidney Crosby, Pittsburgh Penguins, 1; Leon Draisaitl, Oilers, 1
NHL.com staff writer Mike Zeisberger contributed to this report