Playing without Sutter will be more difficult without Edler, who anchors each special-teams unit.
"We've been there, done that, but losing both is tough," Horvat said. "[Edler] plays such a huge role."
Edler's 24:27 of average ice time leads the Canucks, and his 20 points are tops among their defensemen despite being matched up against the opponent's best forwards each game. The return of Hamhuis, who missed almost two months with multiple facial fractures, will help offset the loss, but Vancouver will also have to lean heavily on rookie Ben Hutton in a top-four role for the next six weeks.
"We just got our full D corps back together, and [Edler] goes down," Hutton said. "Guys just have to step up and fill his minutes and hopefully pull together a few big wins."
Hutton played 23:14 in a 2-1 win against the Arizona Coyotes on Wednesday. That's almost five minutes more than his season average, but the 22-year-old said he hardly noticed the extra workload.
"Maybe one game you don't (feel the extra minutes), but over a period of time, it makes a difference," Desjardins said. "It's hard when all of a sudden those minutes increase by three or four a night. People don't think that's big, but it does make a difference and even the quality of ice time. [Christopher] Tanev and Edler lead our team in defensive-zone starts, so all of a sudden you are starting in a different part of the rink more often."
Defenseman Yannick Weber, who was on his way to Utica of the American Hockey League after clearing waivers, will replace Edler on the point of Vancouver's top power-play unit.
"I was ready to go down and fight my way back," Weber said. "All of a sudden, you get the call and you're back up. It kind of feels like it was all just a dream."