The forward is expected to return before the end of the regular season.
"I would term it week to week, lower body. That's where we're at," coach Peter DeBoer said Sunday. "No surgery or anything like that, but he's going to be out for a little bit here."
Stone has 63 points (21 goals, 42 assists) in 65 games, tied with Max Pacioretty for first on the Golden Knights. He's averaging 19:25 of ice time, most among Vegas forwards, entering the game against the Los Angeles Kings at T-Mobile Arena on Sunday (10:30 p.m. ET; NBCSN, NHL.TV). The Golden Knights have won eight in a row and lead the Edmonton Oilers by four points for first place in the Pacific Division.
Stone missed a 4-2 win against the Buffalo Sabres on Friday. He played 19:04 in a 3-0 victory against the Oilers on Feb. 26.
"A guy like him, he really does it all," Golden Knights forward William Karlsson said after the game Friday. "But the one thing that stands out is the ability to create time for himself and us. He's really good taking away the puck."
Chandler Stephenson took Stone's place on a line with Karlsson and Pacioretty.
"We were talking before the third period and we weren't happy with how we were playing," Karlsson said. "We just wanted to go out and make a difference, and we got a goal (by Karlsson that made it 2-1)."
The Golden Knights recalled forward
Brandon Pirri
from Chicago of the American Hockey League on Saturday. He has one assist in 11 games with Vegas and 35 points (15 goals, 20 assists) in 38 games in the AHL.
"I think when you look at the guys we're missing, [forward Alex] Tuch and Stone, some offensive guys, [Pirri is] the one guy down there that has scored at this level and has done it pretty consistently when he's been up here," DeBoer said. "He has an offensive element to him that maybe some of the other guys don't. For me, it's a chance to put a guy in that has some of that ability."
NHL.com independent correspondent Danny Webster contributed to this report