The Kings are in fifth place in the Pacific Division with 71 points, two behind the idle Calgary Flames for the second wild card into the playoffs from the Western Conference. The Golden Knights have the best record in the West and an 11-point lead in the Pacific Division over the second-place San Jose Sharks.
Los Angeles coach John Stevens called the two games against Vegas, which includes a visit to T-Mobile Arena on Tuesday, a "playoff series."
The Golden Knights have won five of their past five games, including a 6-3 win over the Vancouver Canucks on Saturday. Forward Ryan Reaves will make his Vegas debut after being acquired from the Pittsburgh Penguins in a three-team trade involving the Ottawa Senators on Feb. 23.