Evgeni Malkin has been placed on long-term injured reserve retroactive to March 16.
Forwards Drew O'Connor (NHL) and Jonathan Gruden (AHL) have been re-assigned to the taxi squad.
Zucker, 29, has missed the last 18 games with a lower-body injury. The 5-foot-11, 192-pound forward has picked up seven points (4G-3A) in 17 games this season. In 32 games since being acquired from the Minnesota Wild, Zucker has registered 10 goals, nine assists and 19 points.
A native of Newport Beach, California, Zucker has appeared in 488 career NHL games where he's accumulated 262 points (142G-120A).
The Penguins conclude their five-game homestand tonight at 7:00 p.m. against the New York Islanders.