The team has cancelled its annual Halloween-themed activities originally scheduled for Tuesday's 7 p.m. game.
Donations may be made as fans enter each of the arena's three gates.
"The Pittsburgh Penguins join the greater Pittsburgh community in standing up against this senseless violence and supporting the victims and families of the Tree of Life Synagogue," said David Morehouse, president and CEO of the team. "Under these circumstances, we determined it was not appropriate to continue with our annual Halloween theme on Tuesday, so those activities have been cancelled. The entire city has a heavy heart."
A moment of silence will be held before the game.
