On Friday, Weber checked in with his neurosurgeon, Vanderbilt University Medical Center's Dr. Dario J. Englot, to discuss his vastly improved symptoms and mobility - though mainly to ask if he could return to work the next night.
After all, the Sabres were in town, and Weber couldn't possibly miss calling the meeting between his former and current clubs.
Dr. Englot gave the greenlight, and on Saturday Night in Smashville the Voice of the Predators was back in action.
"I think I've said it on the pregame show and again during the intermission about five times, because it is worth repeating," ESPN 102.5 The Game's Max Herz said Saturday. "Pete had actual brain surgery on Monday and is announcing the biggest game that he should be announcing. It's unbelievable… For him to come back right away is not only so impressive, but almost expected. It's the best for everybody, and it has made so many people so happy."
Herz met Weber at the Predators Rookie Showcase in 2014, when he was still an aspiring sportscaster at Vanderbilt University.
"He was the absolute first person I wanted to speak to," Herz said. "And I think for every single person, whether they want to broadcast games or not, Pete would be the best possible reception. If you can't meet a player on the way in, everyone would want to see Pete first at whatever their first Preds event is."
Eight years later, as Weber struggled with the symptoms of his normal pressure hydrocephalus, Herz - now a recognized Nashville sportscaster in his own right - stepped up to the plate for his friend to call Predators road games in his absence.
A daunting task, pinch hitting for the Voice of the Predators?
"Extremely," Herz said.
But as Weber's been known to do in his nearly quarter century with the Predators, as Herz supported his friend on the road, the iconic sportscaster returned the favor.
"Even though Pete was not there, he and [his wife] Claudia could not have been more supportive from afar when we were on the road and up close when we were here," Herz said. "And that's not always how it goes when people temporarily have to stop doing the most important thing in their life. It didn't have to be like that for them, but it could not have been a more welcoming embrace, in every single sense of the word. I can't express it enough."
While Weber is likely still weeks away from returning to the road, the significance of his return to Bridgestone Arena on Saturday was felt throughout the Predators organization.
"He's a legend here," Predators Captain Roman Josi said. "He's unbelievable, just what he's done for this franchise and I think for sports in Nashville and Tennessee. He's such an amazing, amazing person. I've been around him for a long time, and he's always down in the locker room and it's always so great to see him. Like I said, he's such a genuinely nice person and obviously one of the best at what he does. So we're all glad he's back, we're all glad it went well and it's definitely big for the franchise to have him back."