Toronto 1, Detroit 1 (8:24, 1st period)
An Auston Matthews wrister from the slot went off Husso and into the back of the net to tie the game.
Toronto 2, Detroit 1 (9:15, 1st period)
William Nylander scored his 150th career NHL goal on a power play, recording Toronto's first man-advantage tally on its current road trip.
Toronto 3, Detroit 1 (00:52, 2nd period)
Mitchell Marner converted a shot from the slot, extending his point streak to 17 consecutive games.
Toronto 4, Detroit 1 (8:37, 2nd period)
After taking Matthews' pass from just below the Detroit blue line, Rasmus Sandin turned and put a pinpoint wrister past Husso.
Detroit 2, Toronto 4 (12:41, 3rd period)
Seider's shot from the Maple Leafs blue line was tipped in by Erne for his third goal of the season. Ben Chiarot also picked up an assist on Erne's goal.