Miles Wood opened the scoring for New Jersey early in the second period, riding a burst of speed to get behind the Buffalo defense and scoring off his backhand as he cut across the net. The Devils added to their lead 5:31 into the third when Taylor Hall beat Robin Lehner with a shot to his glove side.
The Sabres cut the deficit in half on McCabe's goal, scored with four seconds remaining on their third power play of the night and with 5:02 remaining in regulation. McCabe drew a cross-check from Nico Hischier to put them back on the power play less than two minutes later, opening the door for a comeback.
From that point on, the Sabres got close - Ryan O'Reilly had the best chance at tying the game on a rebound in the crease - but they never did close the gap. Kyle Palmieri sealed the win for the Devils with an empty-net goal in the game's dying seconds.
"We knew what they bring," McCabe said. "They check hard, they skate, they're a really fast team. They're always on top of you, always in your face. We weren't ready to make that next play, and they won a lot more battles than us. Our inconsistent play tonight, you saw the result."
The Sabres had scored a combined nine goals in their last two games, both of which were shutout victories. The difference in production from those games to this one stemmed not from their work in the offensive zone, said alternate captain Jack Eichel, but rather from their own zone.
Eichel thought the Sabres too often opted to break the puck out along the wall, leaving possession up for grabs, as opposed to hitting their open man up the middle.
"I don't think we checked as well," Eichel said. "I thought they played with some good speed. I thought we did a better job of breaking the puck out [on the road trip], which obviously leads to playing in their end, and I don't think we did a very good job of that tonight."
The one goal the Sabres did get - scored by McCabe on a shot from the above the left faceoff circle - came with traffic in front of Devils goaltender Keith Kinkaid, who otherwise had a clear line of vision or had been bailed out by the shot blockers in front of him for much of the night.