Jack Eichel scored the lone goal for the Sabres, which cut the deficit in half early in the second period. The Blues never relented, responding first with a power-play goal from David Perron later in the period and then with a pair of markers from Alexander Steen in the third.
It was the sort of persistent, grinding game that newly acquired forward Michael Frolik came to expect from the reigning Stanley Cup champions during his time in the Western Conference.
"It's always a lot of battles there and they play the right way," Frolik said. "It's never easy against them. … You need to play the ugly game and be kind of patient. When you're behind them, when they're up, they even tighten up more defensively and it's not easy to beat them."
The four-day layover had no effect on Eichel, who extended his point streak to five games. His goal was his 27th in 43 games this season, already just one shy of matching his career high.
The play began with a stretch pass from Rasmus Dahlin to Sam Reinhart, who then delivered a one-touch pass to Eichel as he entered the zone. Eichel squeezed by defenseman Vince Dunn as he wrapped behind the St. Louis net, then buried his shot from the high slot.