The Wild does have good veteran depth at the position however, with Jordie Benn and his 585-game resume perhaps ready to assume a regular role should Dumba and Jon Merrill miss more time.
Merrill has not played in the past three games because of an upper-body injury, but has progressed to the point where he joined the team in the middle of this road trip and has been on the ice for practice.
Still, Dumba will be a tough cog to replace both physically and emotionally. One of the team's alternate captains, Dumba is a leader in the dressing room and on the ice as part of the club's second defensive pairing and it's No. 2 power-play unit.
"He's a huge part of our team and of course we need him," said Wild defenseman Jonas Brodin.
"It's frustrating to lose a guy like that," Foligno said. "He's such a big piece. You can't replace a guy like [that]. It's tough, but hey, we got guys that are waiting (and) excited to play."
St. Louis enters play Friday riding a six-game point streak, rolling up a 5-0-1 record during that stretch.
"Same type of team [as Nashville], they play hard, they play gritty," Evason said. "We're gonna have to be ready [on Friday]."