K'Andre Miller made it 5-3 at 19:36, one-timing Mika Zibanejad's drop pass.
Pitlick made it 6-3 at 1:26 of the third period with a one-timer in front of the net.
"We were forcing a little bit too much, compared to when we were really rolling," Bruins captain Brad Marchand said. "A little bit too much at the blue lines and into the slots instead of holding on to it and making strong plays down low. And then not being tight enough defensively."
Coyle cut it to 6-4 at 2:29 on a give-and-go with James van Riemsdyk.
Panarin scored on a cross-ice feed from Braden Schneider at 4:38 for the 7-4 final.
"We knew where they were in the standings," Miller said. "It was obviously kind of in the back of our head going into this game, but once that puck dropped, I don't think we talked about it too much. I think we got out to our game right away, and the first period kind of set the pace for how we wanted to play for the rest of the game."
The Bruins lost in consecutive days in regulation for the first time since Oct. 27-28, 2021.