Marchenko, who was playing on a line with Gaudreau for the first time, has five goals in 12 games since making his NHL debut on Dec. 6, including three in his past four games.
"It's tough to communicate a little bit," Gaudreau said. "His English isn't the best but we're making it work. He's a great player, a smart player. It's fun to play with him, and hopefully we can create some chemistry and kind of stick together."
Chicago was outshot 14-5 in the second period.
"Stalock made some real unbelievable saves to keep us in the game," Athanasiou said. "It would have been nice to help him out more, but he was huge back there for us."
Nyquist scored his second short-handed goal into an empty net at 19:21 of the third period for the 4-1 final.
NOTES: Gaudreau had 13 assists in December, tying Artemi Panarin (2017) for the most in Columbus history. ... Blue Jackets forward Patrik Laine missed his second straight game (COVID-19 protocol). … Columbus goalie Daniil Tarasov, who was expected to serve as the backup, was a late scratch and is day to day after sustaining an upper-body injury in practice Friday. Elvis Merzlikins backed up Korpisalo after missing three games (illness). … Columbus defenseman Andrew Peeke was a healthy scratch for the first time this season. He played all 82 games in 2021-22. … Blue Jackets defenseman Adam Boqvist had an assist for his first point of the season.